Article

Rbm45 Phylogenetics, Protein Domain Conservation, and Gene Architecture in Clade Metazoa

2024-03-03

Abstract excerpt

Mammalian Rbm45 is predominately expressed in neuronal tissue and is integral in brain development and neuronal differentiation under physiological conditions. Dysregulation of Rbm45 has been strongly associated with neurodegenerative disorders in humans and can drive hepatocellular carcinoma through reprogramming lipid metabolism. Intriguingly, Rbm45 is an ancient protein, evolutionarily conserved throughout meta...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 814a3249-502c-56bb-99a1-221f03f87a54
DOI: 10.1101/2024.02.29.582754

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Rbm45 Phylogenetics, Protein Domain Conservation, and Gene Architecture in Clade MetazoaDOI 10.1101/2024.02.29.582754Read

Molecular Genetic Analysis of Rbm45/Drbp1: Genomic Structure, Expression, and EvolutionSemantic proximity Read

Evolutionary diversification of the BetaM interactome acquired through co-option of the ATP1B4 gene in placental mammals.Semantic proximity Read

RBM10: Structure, functions, and associated diseases.Semantic proximity Read

Human protein-RNA interaction network is highly stable across mammals.Semantic proximity Read

Functional Domains and Evolutionary History of the PMEL and GPNMB Family Proteins.Semantic proximity Read

RNA-Binding Motif Protein 3 as a Therapeutic and Prognostic Target for Drug DiscoverySemantic proximity Read

The diversification of the LIM superclass at the base of the metazoa increased subcellular complexity and promoted multicellular specialization.Semantic proximity Read

Nme protein family evolutionary history, a vertebrate perspectiveSemantic proximity Read

A synthesis of over 9,000 mass spectrometry experiments reveals the core set of human protein complexesSemantic proximity Read

Domain structure and transcript diversity of plectin.Semantic proximity Read

Comparative genomics and evolution of proteins involved in RNA metabolism.Semantic proximity Read

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complexSemantic proximity Read