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Pre-existing cancer cells and induced fibroblasts are key cells for early chemoresistance in ovarian cancer

2024-02-06

Abstract excerpt

Chemoresistance has long been a significant but unresolved issue in the treatment of various cancers, including the most deadly gynecological cancer, the high-grade serous ovary cancer (HGSOC). In this study, single nuclei transcriptome analyses were utilized to identify key cells and core networks for chemoresistance in HGSOC patients with different early responses to platinum-based chemotherapy at the single-cel...

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Identifiers and source

Literature Corpus work
810b97b7-7862-540e-990d-53083bdf066a
DOI
10.1101/2024.02.03.24302058
Open publication

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Pre-existing cancer cells and induced fibroblasts are key cells for early chemoresistance in ovarian cancerDOI 10.1101/2024.02.03.24302058
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