Article

Automated leg tracking reveals distinct conserved gait and tremor signatures in <i>Drosophila</i> models of Parkinson’s Disease and Spinocerebellar ataxia 3

2018-09-25

Abstract excerpt

<h4>Summary</h4> Genetic models in Drosophila have made invaluable contributions to our understanding of the molecular mechanisms underlying neurodegeneration. In human patients, some neurodegenerative diseases lead to characteristic movement dysfunctions, such as abnormal gait and tremors. However, it is currently unknown whether similar movement defects occur in the respective fly models, which could be used t...

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Literature Corpus work: 80f237db-be7a-56ca-b80f-bc6426df2601
DOI: 10.1101/425405

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