Article

T cell-mediated protection against lethal SARS-CoV-2 challenge by a synthetic long peptide vaccine targeting conserved CD4+ and CD8+ T cell epitopes

2026-06-24

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> The majority of approved SARS-CoV-2 prophylactic vaccines are based on mRNA or viral vector platforms and act through the induction of neutralizing IgG antibodies against conformational B cell epitopes of the viral Spike (S) protein, as well as the induction of virus-specific T cell responses. <bold>Methods</bold> In this study, we designed a synthetic long...

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Literature Corpus work: 80d15ffa-4d50-5e01-afe8-8bb474c64c82
DOI: 10.21203/rs.3.rs-10017848/v1

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