Article

Sleep Deprivation Potentiates Silica Nanoparticle-Induced Circadian Disruption and Lacrimal Gland Dysfunction in Mice

2025-05-09

Abstract excerpt

<title>Abstract</title> <p>Sleep deprivation and engineered nanomaterials, such as silica nanoparticles, have emerged as potential risk factors for ocular surface disorders, including dry eye disease. However, the mechanisms by which sleep deprivation exacerbates nanoparticle-induced lacrimal gland dysfunction remain unclear. In this study, the combined effects of sleep deprivation and silica nanoparticle exposur...

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Literature Corpus work: 80c63b6e-8f73-5a69-a0bf-4c2dcff196ac
DOI: 10.21203/rs.3.rs-6562058/v1

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