Article

Abnormal trophoblast invasion in early onset preeclampsia: involvement of cystathionine β-synthase, specificity protein 1 and miR-22

2023-03-14

Abstract excerpt

<h4>Introduction</h4> Impaired trophoblast invasion has been observed in early onset Preeclampsia patients (EOPE). Trophoblast cell invasion during human placentation is majorly regulated by the balance between MMPs 2, 9 and their inhibitors [tissue inhibitors of matrix metalloproteinases (TIMPs 1, 2)]. Exogenous NaHS (hydrogen sulphide donor) treatment was shown to significantly increase the expression levels of...

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Literature Corpus work: 80c3be18-02c1-50fb-bff5-dc63de19a7bf
DOI: 10.1101/2023.03.08.531728

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