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Article

Altered expression of ADM and ADM2 by hypoxia regulates migration of trophoblast and HLA-G expression†

30 Sept 2020

Abstract excerpt

Preeclampsia (PE) is a placental disorder caused by endothelial dysfunction via trophoblast inadequate invasion activity. Adrenomedullin (ADM) and ADM2 are multifunctional peptides that can support vascular activity and placental growth. However, correlation between ADMs and trophoblast functions is currently unclear. The objective of this study was to analyze changes in expression of ADMs in placenta and...

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PMID: 32997116
DOI: 10.1093/biolre/ioaa178

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