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Article

Integrated relationship of nasopharyngeal airway host response and microbiome associates with bronchiolitis severity

30 Aug 2022

Abstract excerpt

Bronchiolitis is a leading cause of infant hospitalizations but its immunopathology remains poorly understood. Here we present data from 244 infants hospitalized with bronchiolitis in a multicenter prospective study, assessing the host response (transcriptome), microbial composition, and microbial function (metatranscriptome) in the nasopharyngeal airway, and associate them with disease severity. We investigate...

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PMID: 36042194
DOI: 10.1038/s41467-022-32323-y

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