Article

Levamisole suppresses activation and proliferation of human T cells by the induction of a p53-dependent DNA damage response

2023-05-09

Abstract excerpt

Levamisole (LMS) is a small molecule used in the treatment of idiopathic nephrotic syndrome (INS). The pathogenesis of INS remains unknown, but most evidence points towards an immunological basis of the disease. Recently, LMS has been shown to increase the relapse-free survival in INS patients treated in combination with corticosteroids with relatively few side effects. While LMS has been hypothesized to exert an...

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Literature Corpus work: 804661c9-d828-5250-8e4c-bfb0ca82e594
DOI: 10.1101/2023.05.08.539819

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