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New SPRi Biosensors for Simultaneous Detection of Tau Protein Isoforms—The Importance of The ptau181/Total Tau Ratio in Alzheimer's Disease

2025-12-22

Abstract excerpt

Tau protein is a nonspecific marker of neurodegeneration, and its phosphorylated form, ptau-181, is specifically associated with Alzheimer's disease (AD). Calculating the ratio of the phosphorylated form to total tau protein can help distinguish AD from other tauopathies or neurodegeneration, as well as reduce the impact of individual differences in total tau protein levels. This also allows for monitoring and com...

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Literature Corpus work
8040e086-d7ba-5b30-9947-a3128e169777
DOI
10.20944/preprints202512.1959.v1
Open publication

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New SPRi Biosensors for Simultaneous Detection of Tau Protein Isoforms—The Importance of The ptau181/Total Tau Ratio in Alzheimer's DiseaseDOI 10.20944/preprints202512.1959.v1
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