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Brain Transcriptome of Autism Spectrum Disorders and Tourette Syndrome Defines Common Targetable Inflammatory Pathways Involving Cytokines, Complement, and Kinase Signalling

2021-09-21

Abstract excerpt

<h4>Background: </h4> Neurodevelopmental disorders (NDDs), including autism-spectrum disorders (ASD) and Tourette syndrome (TS) are common brain conditions which often co-exist, however current management focuses on symptom mitigation, with no approved treatments targeting disease mechanisms. There is accumulating literature implicating the immune system in NDDs, and transcriptomics of post-mortem brain tissue fro...

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Literature Corpus work
8034a363-f913-5ac2-b246-cbd8ed8e454e
DOI
10.21203/rs.3.rs-885680/v1
Open publication

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Brain Transcriptome of Autism Spectrum Disorders and Tourette Syndrome Defines Common Targetable Inflammatory Pathways Involving Cytokines, Complement, and Kinase SignallingDOI 10.21203/rs.3.rs-885680/v1
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