Article

Novel cellular systems unveil mucosal melanoma initiating cells and a role for PI3K/Akt/mTOR pathway in mucosal melanoma fitness.

2023-07-20

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Mucosal Melanomas (MM) are highly aggressive neoplasms arising from mucosal melanocytes. Current treatments offer a limited survival benefit for patients with advanced MM; moreover, the lack of pre-clinical cellular systems has significantly limited the understanding of their immunobiology. <bold>Methods:</bold> Five novel cell lines were obtained from patient-d...

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Literature Corpus work: 8033b910-5580-5ed7-8419-71876c908729
DOI: 10.21203/rs.3.rs-3160482/v1

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