Article

Sex differences in the tumor promoting effects of tobacco smoke in a cRaf transgenic lung cancer disease model

2023-08-28

Abstract excerpt

<h4>Background: </h4> Tobacco smoke (TS) is the leading cause for lung cancer (LC), and female smokers are at a greater risk for LC. Yet, the underlying causes are unknown. Methods We performed whole genome scans in TS exposed wild type and histologically characterized tumor lesions of cRaf transgenic mice. We constructed miRNA-gene and transcription factor-miRNA/gene regulatory networks and determined sex-specif...

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Literature Corpus work: 80239a8a-25a0-5ac8-b1fb-2e9f2c4fa32d
DOI: 10.21203/rs.3.rs-3286488/v1

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