Article

Cannabinoid CB2R regulates T cell gut-homing in preclinical Crohns model.

2025-09-10

Abstract excerpt

Leukocyte trafficking is a critical step in development of chronic intestinal diseases such as Crohn's disease. While strategies that block gut-homing have yielded partial success, this disease remains uncurable, leaving an unmet clinical need. This is the first paper to describe a role for cannabinoid receptor two (CB2R) signalling in promoting retinoic acid-mediated induction of the gut-homing associated integri...

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Literature Corpus work: 801e0a37-615a-5d5a-b106-2de7058d6e2f
DOI: 10.1101/2025.09.05.674422

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