Article

Sex-specific dissection of adiposity genetics reveals distinct pathways to endometrial cancer risk

2026-03-31

Abstract excerpt

Excess adiposity accounts for up to 60% of endometrial cancer cases, yet the mechanisms linking adiposity to carcinogenesis and the relevance of sex-specific adiposity genetics to disease risk have been largely unexplored. Using genomic structural equation modelling of six adiposity genome-wide association studies (GWAS), we perform the first sex-stratified adiposity common factor GWAS model, combining data from 2...

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Literature Corpus work: 800de0b6-c5aa-5986-8c37-83828ecc419a
DOI: 10.64898/2026.03.29.26349665

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