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Upper airway gene expression reveals a more robust innate and adaptive immune response to SARS-CoV-2 in children compared with older adults

2021-08-26

Abstract excerpt

<title>Abstract</title> <p>Unlike other respiratory viruses, SARS-CoV-2 disproportionately causes severe disease in older adults and only rarely in children. To investigate whether differences in the upper airway immune response could contribute to this disparity, we compared nasopharyngeal gene expression in 83 children (<19-years-old; 38 with SARS-CoV-2, 11 with other respiratory viruses, 34 with no virus) and...

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Literature Corpus work
7fe01e9a-8c6b-5dfd-8b63-cbcf59190d81
DOI
10.21203/rs.3.rs-784784/v1
Open publication

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Upper airway gene expression reveals a more robust innate and adaptive immune response to SARS-CoV-2 in children compared with older adultsDOI 10.21203/rs.3.rs-784784/v1
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