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Hydroxyurea in the sickle cell disease modern era

13 Aug 2024

Abstract excerpt

INTRODUCTION: Sickle cell disease is an inherited disorder characterized by hemoglobin S polymerization leading to vaso-occlusion and hemolytic anemia. These result in a variety of pathological events, causing both acute and chronic complications. Millions around the world are affected by sickle cell disease with predominance in sub-Saharan Africa. Hydroxyurea was the first drug approved for use in sickle cell...

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PMID: 39135533
DOI: 10.1080/17512433.2024.2390915

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