Back to search

Article

Microbial Cysteine Degradation Drives Cryptic Sulfide Redox Chemistry in the Gut

2021-10-01

Abstract excerpt

<title>Abstract</title> <p>Although microbial biochemistry shapes a dynamic environment in the gut, how bacterial metabolites such as hydrogen sulfide (H<sub>2</sub>S) mechanistically alter the gut chemical landscape is poorly understood. Here we show for the first time that H<sub>2</sub>S generated during cysteine metabolism drives the reduction of azo (R-N=N-R’) xenobiotics in bacterial cultures, human fecal mi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7f4fc053-6c7d-5a2c-9de4-32a6d2f1946d
DOI
10.21203/rs.3.rs-909548/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Microbial Cysteine Degradation Drives Cryptic Sulfide Redox Chemistry in the GutDOI 10.21203/rs.3.rs-909548/v1
The global anaerobic metabolism regulator <i>fnr</i> is necessary for the degradation of food dyes and drugs by <i>Escherichia coli</i>Semantic proximity
The capacity to produce hydrogen sulfide (H <sub>2</sub> S) via cysteine degradation is ubiquitous in the human gut microbiomeSemantic proximity
Microbial Assimilatory Sulfate Reduction-Mediated H2S: An Overlooked Role in Crohn's Disease DevelopmentSemantic proximity
The Capacity to Produce Hydrogen Sulfide (H2S) via Cysteine Degradation Is Ubiquitous in the Human Gut MicrobiomeSemantic proximity
Sulfoquinovose is exclusively metabolized by the gut microbiota and degraded differently in mice and humansSemantic proximity
Metabolic engineering of <i>Escherichia coli</i> to modulate hydrogen sulfide levels in the mammalian gutSemantic proximity
The Role of Bacteria-Derived Hydrogen Sulfide in Multiple Axes of DiseaseSemantic proximity
Diversity and Distribution of Sulfur Metabolism 1 in the Human Gut Microbiome and its Association with Colorectal CancerSemantic proximity
Diversity and distribution of sulfur metabolism in the human gut microbiome and its association with colorectal cancerSemantic proximity
Engineered bacteria titrate hydrogen sulfide and induce concentration-dependent effects on the host in a gut microphysiological systemSemantic proximity
Recent Advances in Metabolic Pathways of Sulfate Reduction in Intestinal BacteriaSemantic proximity
Engineered bacteria titrate hydrogen sulfide and induce concentration-dependent effects on host in a gut microphysiological systemSemantic proximity
Select a neighboring publication to make it the new centre.