Article

Cross-species ncRNA annotation using synteny-constrained embedding similarity

2026-07-17

Abstract excerpt

<title>Abstract</title> <p>Reference-based annotation transfer has been highly successful for protein-coding genes but remains difficult for non-coding RNAs (ncRNAs), which often show weak sequence conservation, ambiguous transcript boundaries, and incomplete cross-species annotation. Here we present CURIA, a pipeline for cross-species ncRNA annotation that combines genome alignment chains with representations fr...

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Literature Corpus work: 7f2651e7-897a-56a8-96e0-254476d4de03
DOI: 10.21203/rs.3.rs-10374295/v1

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