Article

Combining DNA and protein alignments to improve genome annotation with LiftOn

2024-05-17

Abstract excerpt

As the number and variety of assembled genomes continues to grow, the number of annotated genomes is falling behind, particularly for eukaryotes. DNA-based mapping tools help to address this challenge, but they are only able to transfer annotation between closely-related species. Here we introduce LiftOn, a homology-based software tool that integrates DNA and protein alignments to enhance the accuracy of genome-sc...

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Literature Corpus work: 854cb37f-2f9c-53a6-b08e-cf5026c6db29
DOI: 10.1101/2024.05.16.593026

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