Article
VISUALIZING RETINAL PIGMENT EPITHELIUM PHENOTYPES IN THE TRANSITION TO ATROPHY IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.
Retina (Philadelphia, Pa.) - 1 Dec 2016
Zanzottera Emma C, Ach Thomas, Huisingh Carrie, Messinger Jeffrey D, Freund K Bailey, Curcio Christine A
Abstract excerpt
PURPOSE: To enable future studies of retinal pigment epithelium (RPE) fate in the macular atrophy occurring in eyes with neovascular age-related macular degeneration (nvAMD), the authors determined how RPE morphology changes across the transition from health to atrophy in donor eyes with nvAMD. METHOD: In RPE-Bruch membrane flat mounts of 5 nvAMD eyes, the terminations of organized RPE cytoskeleton and...
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