Article

Adenovirus-specific T cells in adults are frequent, cross-reactive to common childhood adenovirus infections and boosted by adenovirus-vectored vaccines

2024-04-26

Abstract excerpt

Human adenoviruses (HAdVs) cause diverse disease presentations as pathogens, and are also used as viral vectors for vaccines and gene therapy products. Preexisting adaptive immune responses to HAdV are known to influence symptom severity, viral clearance and the success of viral vectored products. Of note, approximately 50% of the UK’s adult population has received at least one dose of a chimpanzee adenovirus vect...

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Literature Corpus work: 7f158469-c2ee-5b5e-a003-6ef914b08078
DOI: 10.1101/2024.04.25.24306332

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