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Decoding the biology and clinical implication of neutrophils in intracranial aneurysm

5 Feb 2024

Abstract excerpt

OBJECTIVE: Abundant neutrophils have been identified in both ruptured and unruptured intracranial aneurysm (IA) domes, with their function and clinical implication being poorly characterized. MATERIALS AND METHODS: We employed single-cell RNA sequencing (scRNA-Seq) datasets of both human and murine model, and external bulk mRNA sequencing datasets to thoroughly explore the features and functional heterogeneous of...

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Share to Intracranial Aneurysms: Treatment and Complications
Share to Neuroinflammation and Neurodegeneration Mechanisms
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms

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PMID: 38317016
DOI: 10.1002/acn3.52014

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