Back to search

Article

Development of properly-polarized trophoblast stem cell-derived organoids to model early human pregnancy

2023-10-03

Abstract excerpt

<h4>Summary</h4> The development of human trophoblast stem cells (hTSC) and stem cell-derived trophoblast organoids has enabled investigation of placental physiology and disease and early maternal-fetal interactions during a stage of human pregnancy that previously had been severely restricted. A key shortcoming in existing trophoblast organoid methodologies is the non-physiologic position of the syncytiotrophobl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7ebda81c-4f30-5464-84e6-e70bbebe1ee0
DOI
10.1101/2023.09.30.560327
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Development of properly-polarized trophoblast stem cell-derived organoids to model early human pregnancyDOI 10.1101/2023.09.30.560327
Development of apical out trophoblast stem cell derived organoids to model early human pregnancySemantic proximity
Exploring maternal-fetal interface with in vitro placental and trophoblastic modelsSemantic proximity
A comprehensive review of human trophoblast fusion models: recent developments and challengesSemantic proximity
Generating Functional Multicellular Organoids from Human Placenta VilliSemantic proximity
Characterization of primary models of human trophoblastSemantic proximity
Modeling human trophoblast, the placental epithelium at the maternal fetal interfaceSemantic proximity
Trophoblast stem cell-based organoid models of the human placental barrierSemantic proximity
Trophoblast Organoids: Capturing the Complexity of Early Placental Development In VitroSemantic proximity
Advancing Human Placental Modeling Through Stem-Cell-Derived Trophoblast Organoids and Reprogramming InnovationsSemantic proximity
A Comprehensive Roadmap of Human Placental Development <i>in vitro</i>Semantic proximity
Trophoblast organoids with physiological polarity model placental structure and functionSemantic proximity
Development of a human iPSC-derived placental barrier-on-chip modelSemantic proximity
Select a neighboring publication to make it the new centre.