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Trophoblast stem cell-based organoid models of the human placental barrier

8 Feb 2024

Abstract excerpt

Human placental villi have essential roles in producing hormones, mediating nutrient and waste exchange, and protecting the fetus from exposure to xenobiotics. Human trophoblast organoids that recapitulate the structure of villi could provide an important in vitro tool to understand placental development and the transplacental passage of xenobiotics. However, such organoids do not currently exist. Here we...

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PMID: 38332125
DOI: 10.1038/s41467-024-45279-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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