Article

Mitochondrial Enzymes of the Urea Cycle Cluster at the Inner Mitochondrial Membrane

2020-05-21

Abstract excerpt

Mitochondrial enzymes involved in energy transformation are organized into multiprotein complexes that channel the reaction intermediates for efficient ATP production. Three of the mammalian urea cycle enzymes: N-acetylglutamate synthase (NAGS), carbamylphosphate synthetase 1 (CPS1), and ornithine transcarbamylase (OTC) reside in the mitochondria. Urea cycle is required to convert ammonia into urea and protect the...

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Literature Corpus work: 7e962aab-819e-5517-85e9-66ecc088f8bb
DOI: 10.1101/2020.05.18.102988

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