Article

Single-Cell Dissection of BCAA Metabolism Unveils ACAT1-Dependent CS Acetylation as a Metabolic Checkpoint for Immunosuppression in Prostate Cancer

2026-05-15

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> The catabolism of branched-chain amino acids (BCAA) usually drives the growth of cancer cells, but the role and mechanism of BCAA in the progression of prostate cancer and the formation of the immunosuppressive microenvironment remain unclear. <bold>Methods</bold> In this study, single-cell sequencing technology was used to analyze the compositional differen...

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Literature Corpus work: 7e8f6a52-dd1f-51d0-b761-a1b734bf2a98
DOI: 10.21203/rs.3.rs-9592453/v1

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Single-Cell Dissection of BCAA Metabolism Unveils ACAT1-Dependent CS Acetylation as a Metabolic Checkpoint for Immunosuppression in Prostate CancerDOI 10.21203/rs.3.rs-9592453/v1Read

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