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Metabolic classifications of renal cell carcinoma reveal intrinsic connections with clinical and immune characteristics

24 Feb 2023

Abstract excerpt

Abstract Background Kidney cancer undergoes a dramatic metabolic shift and has demonstrated responsiveness to immunotherapeutic intervention. However, metabolic classification and the associations between metabolic alterations and immune infiltration in Renal cell carcinoma still remain elucidative. Methods Unsupervised consensus clustering was conducted on the TCGA cohorts for metabolic classification. GESA,...

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PMID: 36829161
DOI: 10.1186/s12967-023-03978-y

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