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Integration RNA bulk and single cell RNA sequencing to explore the change of BCAA metabolism-related immune microenvironment and construct prognostic signature in HNSCC

2025-06-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Several studies have demonstrated that impaired metabolism of branched chain amino acids (BCAAs) is related to cancer progression. However, the specific mechanisms underlying BCAA metabolism in head and neck squamous cell carcinoma (HNSCC) remain to be explored. The aim of this study was to identify prognostic genes associated with BCAA metabolism in HNSCC and to...

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Literature Corpus work
851d9952-b80a-58dd-b325-32db740781a6
DOI
10.21203/rs.3.rs-6030799/v1
Open publication

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