Article

Frequency and Prognostic Value of NPM1 Mutations in Sudanese Acute Myeloid Leukemia Patients

2020-05-31

Abstract excerpt

<h4>Introduction</h4> Acute myeloid leukemia (AML) is a malignancy of proliferative, clonal, abnormally, or poorly differentiated cells of the hematopoietic system, characterized by clonal evolution and genetic heterogeneity (Döhner et al , 2015). The molecular genetics of AML regarding the prognosis of patients mainly representing by NPM1. NPM1 is a nucleolar protein that located on chromosome 5q35.1 which shu...

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Literature Corpus work: 7e6547f7-4250-597f-80ed-bd934dcd7531
DOI: 10.1101/2020.05.31.126334

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