Article

Incidence and clinical significance of FLT3 and nucleophosmin mutation in childhood acute myeloid leukemia in Chile.

2024-01-30

Abstract excerpt

<h4>Introduction: </h4> Acute myeloid leukemia (AML) is a heterogeneous disease and about one third do not have evident genetic abnormalities. The mutation of specific molecular markers such as fms-like tyrosine kinase 3 (FTL3) internal tandem duplication (ITD) and nucleophosmin (NPM1) are associated with an adverse and favorable prognosis, respectively. Objective. To determine the prevalence of FLT3/ITD and NPM1...

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Literature Corpus work: f77817c8-cfed-5f6d-b96d-4d4b9cde11bd
DOI: 10.22541/au.170665566.65522551/v1

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