Article

FOXO3a in vascular smooth muscle cell apoptosis

2018-01-01

Abstract excerpt

FOXO3a is a pro-apoptotic transcription factor which shows increased activation in vascular smooth muscle cells (VSMCs) of advanced atherosclerotic plaques, specifically within the intimal layer. Since VSMC apoptosis plays a crucial role in the pathophysiology of atherosclerosis, we investigated the mechanisms underlying FOXO3a-mediated cell death in this particular cell type. We aimed to characterise a novel VSMC...

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Literature Corpus work: 7e471874-acfb-5291-a383-45fb87219c55
DOI: 10.17863/cam.22947

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