Article

CRISPR-Cas is associated with fewer antibiotic resistance genes in bacterial pathogens

2021-04-12

Abstract excerpt

The acquisition of antibiotic resistance genes via horizontal gene transfer is a key driver of the rise in multidrug resistance amongst bacterial pathogens. Bacterial defence systems per definition restrict the influx of foreign genetic material, and may therefore limit the acquisition of antibiotic resistance. CRISPR-Cas adaptive immune systems are one of the most prevalent defences in bacteria, found in roughly...

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Literature Corpus work: bb4c6c41-96ea-5173-a6d4-8fff412c0be7
DOI: 10.1101/2021.04.12.439454

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