Article

Intraoperative copy number profiling from ultra-low coverage long-read sequencing for molecular tumor assessment

2026-07-23

Abstract excerpt

Copy number variations (CNVs) can serve as important clinical biomarkers for tumor classification and stratification. However, the utility of these CNV biomarkers for intraoperative tumor assessment within the timeframe of neurosurgical procedures has remained elusive due to the protracted duration of conventional CNV characterization methods. Here, we introduce CNVisor, a statistical framework for reliable and ro...

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Literature Corpus work: 7e0836e0-4a31-5493-b34a-eac8e3b80fea
DOI: 10.64898/2026.07.21.26358307

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