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Article

Intraoperative DNA methylation classification of brain tumors impacts neurosurgical strategy

1 Jan 2021

Abstract excerpt

BACKGROUND: Brain tumor surgery must balance the benefit of maximal resection against the risk of inflicting severe damage. The impact of increased resection is diagnosis-specific. However, the precise diagnosis is typically uncertain at surgery due to limitations of imaging and intraoperative histomorphological methods. Novel and accurate strategies for brain tumor classification are necessary to support...

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PMID: 34729487
DOI: 10.1093/noajnl/vdab149

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