Back to search

Article

A BONCAT-iTRAQ method enables temporally resolved quantitative profiling of newly synthesised proteins in <i>Leishmania mexicana</i> parasites during starvation

2019-07-24

Abstract excerpt

Adaptation to starvation is integral to the Leishmania life cycle. The parasite can survive prolonged periods of nutrient deprivation both in vitro and in vivo and starvation plays a crucial role in the differentiation of the parasite from the non-infective promastigote form to infective metacyclics. The identification of parasite proteins synthesised during starvation is key to unravelling the molecular mechan...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7de49538-3bd6-5f8b-b26e-ad12b8507a71
DOI
10.1101/713735
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A BONCAT-iTRAQ method enables temporally resolved quantitative profiling of newly synthesised proteins in <i>Leishmania mexicana</i> parasites during starvationDOI 10.1101/713735
Post‐translational modification of cellular proteins during <b><i>Leishmania donovani</i></b> differentiationSemantic proximity
SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani.Semantic proximity
Neglected Tropical Diseases and Omics Science: Proteogenomics Analysis of the Promastigote Stage of <i>Leishmania major</i> ParasiteSemantic proximity
Identification of <i>Leishmania‐</i> specific protein phosphorylation sites by LC‐ESI‐MS/MS and comparative genomics analysesSemantic proximity
Phosphoproteomic Analysis of Differentiating <i>Leishmania</i> Parasites Reveals a Unique Stage-Specific Phosphorylation MotifSemantic proximity
Analyses of protein expression and genetic fitness determinants reveal dynamic pathways active in starved <i>Pseudomonas aeruginosa</i>Semantic proximity
Comparative proteomics analysis of the egg, sparganum, and adult stages of Spirometra mansoniSemantic proximity
Translational profiling of macrophages infected with Leishmania donovani identifies mTOR- and eIF4A-sensitive immune-related transcriptsSemantic proximity
Defeating the trypanosomatid trio: proteomics of the protozoan parasites causing neglected tropical diseasesSemantic proximity
Five-layer systems analysis of <i>Leishmania</i> stage differentiation reveals an essential role for protein degradation in parasite developmentSemantic proximity
Leishmania mexicana phosphoproteomicsSemantic proximity
Omics Approaches in Drug Development against Leishmaniasis: Current Scenario and Future ProspectsSemantic proximity
Select a neighboring publication to make it the new centre.