Back to search

Article

Analyses of protein expression and genetic fitness determinants reveal dynamic pathways active in starved <i>Pseudomonas aeruginosa</i>

2025-09-28

Abstract excerpt

Heterotrophic bacteria rapidly deplete essential macronutrients during growth and must navigate subsequent periods of growth arrest imposed by starvation. Nutrient limitations can be dynamic in nature, requiring ongoing regulatory adjustments involving new protein synthesis despite total biosynthetic activities being dramatically lower than during growth. Here, we have characterized the responses of the opportunis...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e2be5597-f289-5067-9ebe-f2983a79ab33
DOI
10.1101/2025.09.28.678986
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Analyses of protein expression and genetic fitness determinants reveal dynamic pathways active in starved <i>Pseudomonas aeruginosa</i>DOI 10.1101/2025.09.28.678986
Mass spectrometry-based profiling of the carbon starved <i>Escherichia coli</i> proteome reveals upregulation of stress-inducible pathways implicated in biofilm formation and antibiotic resistanceSemantic proximity
A Grad-seq view of RNA and protein complexes in <i>Pseudomonas aeruginosa</i> under standard and bacteriophage predation conditionsSemantic proximity
Phosphorus stress induces the synthesis of novel glycolipids in <i>Pseudomonas aeruginosa</i> that confer protection against a last-resort antibioticSemantic proximity
Zinc Starvation Drives Respiratory Remodeling and Metabolic Adaptations Associated with Cystic Fibrosis in <i>Pseudomonas aeruginosa</i>Semantic proximity
Bacterial proteomics and its role in antibacterial drug discoverySemantic proximity
Functional interplay between (p)ppGpp and RNAP in <i>Acinetobacter baumannii</i>Semantic proximity
Phase-Specific Antibiotic Resistance Mechanisms in an <i>Escherichia coli</i> B StrainSemantic proximity
Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria.Semantic proximity
Genome-wide high-density CRISPR interference screens reveal condition-specific metabolic vulnerabilities in <i>Pseudomonas aeruginosa</i> PAO1Semantic proximity
Genome-wide survey of <i>Pseudomonas aeruginosa</i> PA14 reveals a role for the glyoxylate pathway and extracellular proteases in the limited utilization of mucinSemantic proximity
Critical functions and key interactions mediated by the RNase E scaffolding domain in <i>Pseudomonas aeruginosa</i>Semantic proximity
Systems-wide dissection of organic acid assimilation in <i>Pseudomonas aeruginosa</i> reveals a novel path to underground metabolismSemantic proximity
Select a neighboring publication to make it the new centre.