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Incorporation of genome-bound cellular proteins into HIV-1 particles regulates viral infection

2023-06-14

Abstract excerpt

<h4>SUMMARY</h4> The initial steps of the human immunodeficiency virus 1 (HIV-1) lifecycle are regulated by cellular RNA-binding proteins (RBPs). To understand the scope of these early host-virus interactions, we developed in virion RNA interactome capture (ivRIC), which allowed the comprehensive and systematic profiling of the proteins that interact with the HIV-1 genomic (g)RNA inside viral particles. ivRIC ide...

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Literature Corpus work
7dde90fe-e8fc-573b-807b-4d233adeff16
DOI
10.1101/2023.06.14.544764
Open publication

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Incorporation of genome-bound cellular proteins into HIV-1 particles regulates viral infectionDOI 10.1101/2023.06.14.544764
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