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Personalized mRNA Vaccine Combined with PD-1 Inhibitor Therapy in a Patient with Advanced Esophageal Squamous Cell Carcinoma

2023-08-23

Abstract excerpt

<h4>Background: </h4> Therapeutic cancer vaccines serve as a valuable tool to educate the immune system to fight tumors precisely. Cancer cells have characteristics of genetic instability and rapidly accumulate somatic mutations rapidly, which can result in the production of tumour-specific antigens (TSAs) called neoantigens. The main goal of neoantigen-based cancer vaccines is to activate the immune system and ef...

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Literature Corpus work
7ddbe95a-24cf-5b40-b1e2-336643ce34c8
DOI
10.21203/rs.3.rs-3242165/v1
Open publication

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Personalized mRNA Vaccine Combined with PD-1 Inhibitor Therapy in a Patient with Advanced Esophageal Squamous Cell CarcinomaDOI 10.21203/rs.3.rs-3242165/v1
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