Personalized Neoantigen DNA Cancer Vaccines: Current Status and Future Perspectives

Abstract excerpt

Tumor mutation-derived neoantigens are considered promising targets for cancer immunotherapy. Personalized vaccines have emerged as an approach to deliver neoantigens and thereby trigger the induction of specific T-cell responses that can find and eliminate tumor cells based on the cell-surface presence of neoantigens. To this end, several neoantigen vaccine formats have provided encouraging results in clinical tr...

Topics

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• Immunotherapy and Immune Responses
• Monoclonal and Polyclonal Antibodies Research
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

251b2ddc-253c-5440-bc55-7f5c430d1051

DOI

10.33696/immunology.6.188