Article

A Peptide-Based Neoantigen Vaccine for Patients With Advanced Pancreatic Cancer Refractory to Standard Treatment

2020-12-21

Abstract excerpt

<h4>Background: </h4> Tumor-specific neoantigens are considered as personalized and potential ultimate targets for cancer immunotherapy. Recently, neoantigen cancer vaccines have been designed to train the patient's immune system to specifically target and kill tumor cells. However, the safety and efficacy of neoantigen vaccines in pancreatic cancer treatment remain poorly understood. <h4>Methods: </h4>: Personali...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e497e909-0c62-5e29-97ac-e4d0075e76bf
DOI: 10.21203/rs.3.rs-130888/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Peptide-Based Neoantigen Vaccine for Patients With Advanced Pancreatic Cancer Refractory to Standard TreatmentDOI 10.21203/rs.3.rs-130888/v1Read

Neoantigens in Cancer Immunotherapy: An Overview with a Focus on Non-small Cell Lung Cancer and Pancreatic Ductal Adenocarcinoma.Semantic proximity Read

BCL2A1 neoepitope-elicited cytotoxic T lymphocytes are a promising individualized immunotherapy of pancreatic cancer.Semantic proximity Read

Neoantigen polypeptide vaccines induce effective antitumor response in colorectal cancerSemantic proximity Read

Engineering neoantigen vaccines to improve cancer personalized immunotherapySemantic proximity Read

Personalized mRNA Vaccine Combined with PD-1 Inhibitor Therapy in a Patient with Advanced Esophageal Squamous Cell CarcinomaSemantic proximity Read

Neoantigens: The Novel Precision Cancer ImmunotherapySemantic proximity Read

A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer.Semantic proximity Read

Neoantigen-based personalized cancer vaccines: the emergence of precision cancer immunotherapySemantic proximity Read

Cancer neoantigens as potential targets for immunotherapy.Semantic proximity Read

Trials of vaccines for pancreatic ductal adenocarcinoma: Is there any hope of an improved prognosis?Semantic proximity Read

Current and future therapies for advanced pancreatic cancer.Semantic proximity Read

Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translationSemantic proximity Read