Article

The <i>pcnB</i> gene sustains <i>Shigella flexneri</i> virulence

2025-06-16

Abstract excerpt

<h4>ABSTRACT</h4> The enteropathogen Shigella flexneri employs a Type Three Secretion System (T3SS) to colonize intestinal epithelial cells. Genes encoding the T3SS are located on a large IncFII virulence plasmid, pINV. T3SS expression comes at the expense of slowed Shigella growth and is therefore strictly controlled by both transcriptional and post-transcriptional mechanisms. Following up on a recent genome-w...

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Literature Corpus work: 98e7bc4d-2b2d-5a70-83c4-2b173b907045
DOI: 10.1101/2025.06.16.659909

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