Article

Framing the potential of public frameshift peptides as immunotherapy targets in colon cancer

2020-03-29

Abstract excerpt

Approximately 15% of Colon Cancers are Microsatellite Instable (MSI). Frameshift Peptides (FPs) formed in MSI Colon Cancer are potential targets for immunotherapeutic strategies. Here we comprehensively characterize the mutational landscape of 71 MSI Colon Cancer patients from the cancer genome atlas (TCGA-COAD). We confirm that the mutations in MSI Colon Cancers are frequently frameshift deletions (23% in MSI; 1%...

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Literature Corpus work: 7d9052b9-fac6-5687-9a8b-4c9747bddfed
DOI: 10.1101/2020.03.26.010231

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