Article

Anti-Inflammatory Effects of Idebenone Attenuate Systemic Inflammatory Diseases by Suppressing NF-κB Activation

2023-12-29

Abstract excerpt

Inflammation is a natural protective process through which the immune system responds to injury, infection, or irritation. However, hyperinflammation or long-term inflammatory response can cause various inflammatory diseases. Although idebenone was initially developed for the treatment of cognitive impairment and dementia, it is currently used to treat various diseases. However, its anti-inflammatory effects and r...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7d8b2f67-1dd3-54e8-963c-36e78d68c181
DOI: 10.20944/preprints202312.2310.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Anti-Inflammatory Effects of Idebenone Attenuate Systemic Inflammatory Diseases by Suppressing NF-κB ActivationDOI 10.20944/preprints202312.2310.v1Read

Anti-inflammatory effect of proanthocyanidins from blueberry through NF-κβ/NLRP3 signaling pathway in vivo and in vitroSemantic proximity Read

Inhibition of the TLR4/NF-κB/TNF-α axis by TAK-242 or PDTC reduces central nervous system inflammation to alleviate lipopolysaccharide induced sickness behaviors in miceSemantic proximity Read

Qiang Xin 1 Formula Suppresses Excessive Pro-inflammatory Cytokine Responses and Microglia Activation to Prevent Cognitive Impairment and Emotional Dysfunctions in Experimental SepsisSemantic proximity Read

MicroRNA‑146a improves sepsis‑induced cardiomyopathy by regulating the TLR‑4/NF‑κB signaling pathwaySemantic proximity Read

Repositioning linifanib as a potent anti-necroptosis agent for sepsisSemantic proximity Read

Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavior.Semantic proximity Read

Germacrone attenuates memory impairment, hippocampal inflammation, and neurological deficits induced by Lipopolysaccharide in miceSemantic proximity Read

GENIPOSIDE IMPROVES CLP-INDUCED SEPSIS MODEL PROGNOSIS BY UPREGULATING PPARγ TO MODULATE MONOCYTE PHENOTYPE AND CYTOKINE NETWORK.Semantic proximity Read

Glycyrrhiza Uralensis Polysaccharides Inhibits the cGAS-STING Signaling Pathway and Ameliorates Cecum Ligation and Puncture-induced Sepsis Semantic proximity Read

Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammationSemantic proximity Read

Marein prevented LPS-induced osteoclastogenesis by regulating the NF-κB pathway in vitroSemantic proximity Read

Liang-Ge-San: a classic traditional Chinese medicine formula, attenuates acute inflammation via targeting GSK3βSemantic proximity Read