Article

Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance

2022-01-28

Abstract excerpt

<title>Abstract</title> <p>The accumulation of α-synuclein (α-syn) in intracellular formations known as Lewy bodies (LBs) is associated with several neurodegenerative diseases including Parkinson’s disease and Lewy Body Dementia. There is still limited understanding of how α-syn and the formation of LBs is associated with cellular dysfunction and degeneration in these diseases. To examine the clearance and produc...

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Literature Corpus work: 7d3cbcdb-fe7c-5aea-a481-fba0991c9fdb
DOI: 10.21203/rs.3.rs-1307173/v1

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