Article

Sm-site containing mRNAs can accept Sm-rings and are downregulated in Spinal Muscular Atrophy

2024-10-09

Abstract excerpt

<h4>ABSTRACT</h4> Sm-ring assembly is important for the biogenesis, stability, and function of uridine-rich small nuclear RNAs (U snRNAs) involved in pre-mRNA splicing and histone pre-mRNA processing. Sm-ring assembly is cytoplasmic and dependent upon the Sm-site sequence and structural motif, ATP, and Survival motor neuron (SMN) protein complex. While RNAs other than U snRNAs were previously shown to associate...

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Literature Corpus work: 7d086283-5882-5f4b-b375-bd5723a65b6e
DOI: 10.1101/2024.10.09.617433

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