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Article

SMN in spinal muscular atrophy and snRNP biogenesis

17 Feb 2011

Abstract excerpt

Abstract Ribonucleoprotein (RNP) complexes function in nearly every facet of cellular activity. The spliceosome is an essential RNP that accurately identifies introns and catalytically removes the intervening sequences, providing exquisite control of spatial, temporal, and developmental gene expressions. U‐snRNPs are the building blocks for the spliceosome. A significant amount of insight into the molecular...

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Identifiers

PMID: 21957043
DOI: 10.1002/wrna.76

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The Spinal Muscular Atrophy Disease Gene Product, SMN, and Its Associated Protein SIP1 Are in a Complex with Spliceosomal snRNP ProteinsSemantic proximity Read ↗

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