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SMRT sequencing reveals differential patterns of methylation in two O111:H- Shiga toxigenic <i>Escherichia coli</i> isolates from a historic hemolytic uremic syndrome outbreak in Australia

2017-08-11

Abstract excerpt

Shiga toxigenic Escherichia coli (STEC) are important food-borne pathogens and a major cause of haemorrhagic colitis and haemolytic-uremic syndrome (HUS) worldwide. In 1995 a severe HUS outbreak in Adelaide occurred. A recent genomic analysis of STEC O111:H-strains 95JB1 and 95NR1 from this outbreak found that the more virulent isolate, 95NR1, harboured two additional copies of the Shiga toxin 2 (Stx2) genes alth...

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Literature Corpus work
7cd9b36a-b2dd-5b00-b968-ce59844a8b44
DOI
10.1101/173336
Open publication

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SMRT sequencing reveals differential patterns of methylation in two O111:H- Shiga toxigenic <i>Escherichia coli</i> isolates from a historic hemolytic uremic syndrome outbreak in AustraliaDOI 10.1101/173336
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