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Evolution of a zoonotic pathogen: investigating prophage diversity in enterohaemorrhagic Escherichia coli O157 by long-read sequencing.

Microbial genomics - 1 Dec 2016

Shaaban Sharif, Cowley Lauren A, McAteer Sean P, Jenkins Claire, Dallman Timothy J, Bono James L, Gally David L

Abstract excerpt

Enterohaemorrhagic Escherichia coli (EHEC) O157 is a zoonotic pathogen for which colonization of cattle and virulence in humans is associated with multiple horizontally acquired genes, the majority present in active or cryptic prophages. Our understanding of the evolution and phylogeny of EHEC O157 continues to develop primarily based on core genome analyses; however, such short-read sequences have limited value...

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Identifiers

PMID: 28348836
DOI: 10.1099/mgen.0.000096
PMCID: PMC5359411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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