Article

A novel interaction between the 5’ untranslated region of the Chikungunya virus genome and Musashi RNA binding protein is essential for efficient virus genome replication

2023-03-29

Abstract excerpt

Chikungunya virus (CHIKV) is a re-emerging, pathogenic alphavirus that is transmitted to humans by Aedes spp . mosquitoes—causing fever and debilitating joint pain, with frequent long-term health implications and high morbidity. The CHIKV replication cycle is poorly understood and specific antiviral therapeutics are lacking. In the current study, we identify host cell Musashi RNA binding protein-2 (MSI-2) as a pr...

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Literature Corpus work: 7cc429b7-ded9-5e17-99f4-fc4fe0eff25c
DOI: 10.1101/2023.03.29.534719

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A novel interaction between the 5’ untranslated region of the Chikungunya virus genome and Musashi RNA binding protein is essential for efficient virus genome replicationDOI 10.1101/2023.03.29.534719Read

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